Fig. 6

Decreased level of vWF in venous thrombi in ERp18-KO mice. A ELISA was used to detect the concentration of vWF in the ERp18-KO and WT mice plasma after IVC stenosis. Mean ± SEM, *P < 0.05, ns, not significant, n = 5, t-test. B Mice were subjected to IVC ligation-induced stenosis. Forty-eight hours after the IVC ligation, mice were euthanized, and collected thrombi were processed for tissue sectioning. The sections were than stained with antibodies against vWF. C Thrombus constituents were quantified using integrated density. The scale bar was 500 μm. Mean ± SEM, *P < 0.05, n = 9, t-test