Table 1 Univariate analysis of baseline characteristics and clinical outcome
Characteristics | All patients (n = 3805) | Good outcome (n = 3176) | Poor outcome (n = 629) | P value |
|---|---|---|---|---|
Age (median [IQR]) | 59 (51, 69) | 58 (50, 68) | 66 (55, 76) | < 0.001 |
Sex (male), N (%) | 2676 (70.3) | 2276 (71.7) | 400 (63.6) | < 0.001 |
BMI (median [IQR]) | 24.12 (21.64, 26.25) | 24.22 (21.86, 26.28) | 23.44 (20.67, 25.97) | 0.011 |
Baseline NIHSS score, median (IQR) | 4 (2, 8) | 4 (2, 7) | 10 (5, 14.25) | < 0.001 |
ODT, min (median [IQR]) | 88 (50, 145) | 88 (50, 145) | 88 (48, 148) | 0.915 |
DNT, min (median [IQR]) | 35 (26, 49) | 35 (26, 48) | 35 (27, 50) | 0.364 |
ONT, min (median [IQR]) | 133 (88, 193) | 132 (88, 192) | 138 (87, 195) | 0.569 |
Medical history, n (%) | Â | Â | Â | Â |
 Smoking | 1301 (34.2) | 1110 (34.9) | 191 (30.5) | 0.027 |
 Alcohol drinking | 928 (24.4) | 786 (24.7) | 142 (22.6) | 0.246 |
 Hypertension | 1130 (29.7) | 957 (30.1) | 173 (27.5) | 0.188 |
 Diabetes | 356 (9.4) | 268 (8.4) | 88 (14.0) | < 0.001 |
 Previous stroke | 622 (16.3) | 487 (15.3) | 135 (21.5) | < 0.001 |
Blood pressure, median (IQR) | Â | Â | Â | Â |
 Systolic blood pressure, mmHg | 148 (132, 163) | 147 (132, 162) | 150 (134, 165) | 0.106 |
 Diastolic blood pressure, mmHg | 88 (79, 98) | 88 (80, 98) | 87 (78, 97) | 0.019 |
Laboratory examination, median (IQR) | Â | Â | Â | Â |
 Serum glucose, mmol/L | 5.90 (5.05, 7.42) | 5.80 (5.00, 7.11) | 6.71 (5.50, 8.95) | < 0.001 |
 LDL-C, mmol/L | 2.90 (2.28, 3.54) | 2.92 (2.29, 3.53) | 2.82 (2.23, 3.56) | 0.163 |
 Neutrophil, 109/L | 4.80 (3.69, 6.60) | 4.71 (3.63, 6.47) | 5.32 (4.03, 7.50) | < 0.001 |
 Lymphocyte, 109/L | 2.00 (1.45, 2.72) | 2.05 (1.50, 2.75) | 1.82 (1.26, 2.57) | < 0.001 |
 hs-CRP, mg/L | 1.68 (0.55, 4.60) | 1.51 (0.50, 4.11) | 2.50 (0.84, 7.60) | < 0.001 |
 Fibrinogen, mg/dL | 2.99 (2.52, 3.57) | 2.95 (2.49, 3.52) | 3.13 (2.66, 3.84) | < 0.001 |
 D-dimer, mg/L | 0.44 (0.22, 1.38) | 0.40 (0.22, 1.17) | 0.90 (0.30, 2.61) | < 0.001 |
 HbA1c, % | 5.90 (5.60, 6.50) | 5.90 (5.50, 6.40) | 6.10 (5.60, 7.20) | < 0.001 |
 ALT, U/L | 20 (15, 29) | 21 (15, 29) | 19 (14, 25) | < 0.001 |
 Cystatin C, mg/L | 1.00 (0.81, 1.34) | 1.00 (0.81, 1.34) | 1.00 (0.82, 1.33) | 0.849 |
 Serum uric acid, µmol/L | 348.63 (285.90, 426.00) | 351.00 (287.90, 429.25) | 337.00 (271.10, 408.70) | 0.001 |
 Serum creatinine, µmol/L | 74.20 (62.00, 88.50) | 74.10 (62.00, 88.00) | 74.90 (61.40, 92.00) | 0.411 |
 BUN, mmol/L | 5.41 (4.34, 6.71) | 5.39 (4.31, 6.61) | 5.60 (4.46, 7.32) | 0.001 |
 Hcy, µmol/L  Hcy, µmol/L | 11.90 (9.5, 15.40) | 11.80 (9.40, 15.30) | 12.16 (9.90, 16.00) | 0.074 |