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Table 5 Prediction metrics of NEWS2 cut-offs for advanced intervention (secondary outcome)*

From: Association of initial national early warning score with clinical deterioration in pulmonary embolism

Variable

Sensitivity

Specificity

PPV

NPV

AUC

OR

NEWS2

≥ 3

0.78 (0.74, 0.81)

0.49 (0.47, 0.52)

0.31 (0.29, 0.34)

0.88 (0.86, 0.90)

0.63 (0.30, 0.70

3.3 (2.6, 4.2)

NEWS2

≥ 4

(Youden’s optimal cut-off)

0.64 (0.59, 0.68)

0.63 (0.61, 0.65)

0.34 (0.31, 0.37)

0.85 (0.83, 0.87)

0.63 (0.24, 0.76)

3.0 (2.4, 3.6)

NEWS2

≥ 5

0.51 (0.46, 0.55)

0.74 (0.72, 0.77)

0.37 (0.34, 0.41)

0.84 (0.82, 0.85)

0.63 (0.21, 0.79)

3.0 (2.4, 3.7)

  1. * Abbreviations: PE = pulmonary embolism PPV = positive predictive value, NPV = negative predictive value, AUC = area under the curve OR = odds ratio
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Thrombosis Journal

ISSN: 1477-9560

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